Assessment of melanogenesis in a pigmented human tissue-cultured skin equivalent
نویسندگان
چکیده
منابع مشابه
Human Skin Equivalent Model
Skin, the largest organ in the body, performs many important roles including protection against physical and chemical insults, regulation of temperature and fluid loss, and immunity and sensory roles. Once damaged, skin cannot perform these normal tasks and numerous complications such as infection or fluid loss can occur. To restore these roles, the body needs to close the wound as quickly as p...
متن کاملIn vitro reconstruction of a human capillary-like network in a tissue-engineered skin equivalent.
For patients with extensive burns, wound coverage with an autologous in vitro reconstructed skin made of both dermis and epidermis should be the best alternative to split-thickness graft. Unfortunately, various obstacles have delayed the widespread use of composite skin substitutes. Insufficient vascularization has been proposed as the most likely reason for their unreliable survival. Our purpo...
متن کاملSkin Equivalent Tissue-Engineered Construct: Co-Cultured Fibroblasts/ Keratinocytes on 3D Matrices of Sericin Hope Cocoons
The development of effective and alternative tissue-engineered skin replacements to autografts, allografts and xenografts has became a clinical requirement due to the problems related to source of donor tissue and the perceived risk of disease transmission. In the present study 3D tissue engineered construct of sericin is developed using co-culture of keratinocytes on the upper surface of the f...
متن کاملBehavior of tissue-engineered skin: a comparison of a living skin equivalent, autograft, and occlusive dressing in human donor sites.
OBJECTIVE To compare the behavior of a tissue-engineered living skin equivalent (LSE) with an autograft in acute donor site wounds. DESIGN Paired-comparison, randomized control trial. SETTING A university dermatology service. PATIENTS Three donor sites were created on the anterior thigh of each of 20 patients requiring split-thickness skin grafts. INTERVENTION For each patient, the dono...
متن کاملassessment of deep word knowledge in elementary and advanced iranian efl learners: a comparison of selective and productive wat tasks
testing plays a vital role in any language teaching program. it allows teachers and stakeholders, including program administrators, parents, admissions officers and prospective employers to be assured that the learners are progressing according to an accepted standard (douglas, 2010). the problems currently facing language testers have both practical and theoretical implications but the first i...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2019
ISSN: 0019-5154
DOI: 10.4103/ijd.ijd_410_17